Single Exposure of Bisphenol A (BPA) Affects Newborn Mouse Brain — Longterm Increases in Hyperactivity and Cognitive Effects

27Oct11

Viberg of the Eriksson lab in Sweden shows in a new paper in Toxicology (full text) that a single exposure to BPA on postnatal day 10 has dose-dependent effects. (Mice sexually mature around p45.)

The paper is still in press, so details are sparse, but authors saw changes in spontaneous behavior when exposed to a new environment, minor changes in cholenergic-system mediated behavior (responses to nicotine), but no changes in the spatial memory (Morris Water maze) or anxiety (elevated plus maze).
Here is a further article from science direct that includes quotes from the authors.

BPA was previously known to increase the risk of trisomies which cause disorders such as Down Syndrome–Full Text. It is extremely important to consider the risks since elevated levels are found in many environmental sources from receipts, plastic water bottles, canned foods, and even dentistry. BPA accumulates in the body over time, so it is important to be careful, especially if you are a woman planning on having children.

It is also important to note that hyperactivity in mice refers to increased activity and locomotion, which could result from many things and may have little or no relationship to the type of hyperactivity observed in children with ADHD.

—–

If you are interested in the effects of hormones on the brain, check out my post: MPA, the Hormone used in the Depo Provera birth control shot, causes memory problems in rats

About these ads


No Responses Yet to “Single Exposure of Bisphenol A (BPA) Affects Newborn Mouse Brain — Longterm Increases in Hyperactivity and Cognitive Effects”

  1. Leave a Comment

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s


Follow

Get every new post delivered to your Inbox.

Join 46 other followers